A major limitation of most modeling and simulation tools is that only subject matter experts can use them. Pfizer has overcome this limitation by using EASA’s patented “application” technology to create a proprietary “app store” of intuitive web apps that drive a wide variety of models created with tools such as gPROMS, Aspen Plus, DynoChem, Fluent, and MATLAB, as well as in-house codes and scripts. These web apps incorporate both expertise and comprehensive error checks, enabling users who are not familiar with the underlying modeling tools to safely use them.